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Automated Pipeline for Purification, Biophysical and X-Ray Analysis of Biomacromolecular Solutions

Small angle X-ray scattering (SAXS), an increasingly popular method for structural analysis of biological macromolecules in solution, is often hampered by inherent sample polydispersity. We developed an all-in-one system combining in-line sample component separation with parallel biophysical and SAX...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Graewert, Melissa A., Franke, Daniel, Jeffries, Cy M., Blanchet, Clement E., Ruskule, Darja, Kuhle, Katja, Flieger, Antje, Schäfer, Bernd, Tartsch, Bernd, Meijers, Rob, Svergun, Dmitri I.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5377070/
https://ncbi.nlm.nih.gov/pubmed/26030009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10734
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