SDF-1/CXCR4 Signaling Maintains Stemness Signature in Mouse Neural Stem/Progenitor Cells

SDF-1 and its primary receptor, CXCR4, are highly expressed in the embryonic central nervous system (CNS) and play a crucial role in brain architecture. Loss of SDF-1/CXCR4 signaling causes abnormal development of neural stem/progenitor cells (NSCs/NPCs) in the cerebellum, hippocampus, and cortex. H...

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Publicat a:Stem Cells Int
Autors principals: Ho, Shih-Yin, Ling, Thai-Yen, Lin, Hsing-Yu, Liou, Jeffrey Tsai-Jui, Liu, Fei-Chih, Chen, I-Chun, Lee, Sue-Wei, Hsu, Yu, Lai, Dar-Ming, Liou, Horng-Huei
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376953/
https://ncbi.nlm.nih.gov/pubmed/28408934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/2493752
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