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Antiepileptic Drugs Impair Shortening of Isolated Cardiomyocytes

BACKGROUND: Most antiepileptic drugs (AEDs) inhibit seizure generation by acting on voltage-dependent ion channels. Voltage-dependent sodium and calcium channels are commonly expressed in brain and heart, suggesting that AEDs may have considerable cardiodepressive effects, thereby facilitating sudde...

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Detalhes bibliográficos
Publicado no:Front Neurol
Main Authors: Hulbert, Johanna, Elger, Christian E., Meyer, Rainer, Surges, Rainer
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376916/
https://ncbi.nlm.nih.gov/pubmed/28421035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2017.00133
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