Deficient Adipogenesis of Scleroderma Patient and Healthy African American Monocytes

Monocytes from systemic sclerosis (SSc, scleroderma) patients and healthy African Americans (AA) are deficient in the regulatory protein caveolin-1 leading to enhanced migration toward chemokines and fibrogenic differentiation. While dermal fibrosis is the hallmark of SSc, loss of subcutaneous adipo...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Autores principales: Lee, Rebecca, Reese, Charles, Carmen-Lopez, Gustavo, Perry, Beth, Bonner, Michael, Zemskova, Marina, Wilson, Carole L., Helke, Kristi L., Silver, Richard M., Hoffman, Stanley, Tourkina, Elena
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376579/
https://ncbi.nlm.nih.gov/pubmed/28420992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00174
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