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Estimating Systemic Exposure to Levonorgestrel from an Oral Contraceptive

OBJECTIVE: The gold standard for measuring oral contraceptive (OC) pharmacokinetics is the 24-hour steady-state area-under-the-curve (AUC). We conducted this study to assess whether limited sampling at steady state or measurements following use of one or two OCs could provide an adequate proxy in ep...

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Détails bibliographiques
Publié dans:Contraception
Auteurs principaux: Basaraba, Cale N, Westhoff, Carolyn L, Pike, Malcolm C, Nandakumar, Renu, Cremers, Serge
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376510/
https://ncbi.nlm.nih.gov/pubmed/28041990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.contraception.2016.12.007
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