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Ribosome assembly in trypanosomatids: A novel therapeutic target

In Liu et al., the authors present a 2.5-Å structure of the Trypanosoma cruzi 60S ribosomal subunit and propose a model for the stepwise assembly of the large subunit ribosomal RNA (rRNA). Based on this study, we discuss how the unique features of trypanosomatid ribosome assembly offer potential dru...

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Publicat a:Trends Parasitol
Autors principals: Kamina, Anyango D., Williams, Noreen
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376504/
https://ncbi.nlm.nih.gov/pubmed/27988096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pt.2016.12.003
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