Prospective identification of hematopoietic lineage choice by deep learning

Differentiation alters molecular properties of stem and progenitor cells, leading to changing shape and movement characteristics. We present a deep neural network that prospectively predicts lineage choice in differentiating primary hematopoietic progenitors, using image patches from brightfield mic...

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Pubblicato in:Nat Methods
Autori principali: Buggenthin, Felix, Buettner, Florian, Hoppe, Philipp S, Endele, Max, Kroiss, Manuel, Strasser, Michael, Schwarzfischer, Michael, Loeffler, Dirk, Kokkaliaris, Konstantinos D, Hilsenbeck, Oliver, Schroeder, Timm, Theis, Fabian J, Marr, Carsten
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376497/
https://ncbi.nlm.nih.gov/pubmed/28218899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.4182
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