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Thiol trapping and metabolic redistribution of sulfur metabolites enable cells to overcome cysteine overload

Cysteine is an essential requirement in living organisms. However, due to its reactive thiol side chain, elevated levels of intracellular cysteine can be toxic and therefore need to be rapidly eliminated from the cellular milieu. In mammals and many other organisms, excess cysteine is believed to be...

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Detalhes bibliográficos
Publicado no:Microb Cell
Main Authors: Deshpande, Anup Arunrao, Bhatia, Muskan, Laxman, Sunil, Bachhawat, Anand Kumar
Formato: Artigo
Idioma:Inglês
Publicado em: Shared Science Publishers OG 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376351/
https://ncbi.nlm.nih.gov/pubmed/28435838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/mic2017.04.567
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