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Thiol trapping and metabolic redistribution of sulfur metabolites enable cells to overcome cysteine overload

Cysteine is an essential requirement in living organisms. However, due to its reactive thiol side chain, elevated levels of intracellular cysteine can be toxic and therefore need to be rapidly eliminated from the cellular milieu. In mammals and many other organisms, excess cysteine is believed to be...

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Bibliografiske detaljer
Udgivet i:Microb Cell
Main Authors: Deshpande, Anup Arunrao, Bhatia, Muskan, Laxman, Sunil, Bachhawat, Anand Kumar
Format: Artigo
Sprog:Inglês
Udgivet: Shared Science Publishers OG 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376351/
https://ncbi.nlm.nih.gov/pubmed/28435838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/mic2017.04.567
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