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Novel phosphate-activated macrophages prevent ectopic calcification by increasing extracellular ATP and pyrophosphate

PURPOSE: Phosphorus is an essential nutrient involved in many pathobiological processes. Less than 1% of phosphorus is found in extracellular fluids as inorganic phosphate ion (Pi) in solution. High serum Pi level promotes ectopic calcification in many tissues, including blood vessels. Here, we stud...

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Veröffentlicht in:PLoS One
Hauptverfasser: Villa-Bellosta, Ricardo, Hamczyk, Magda R., Andrés, Vicente
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376322/
https://ncbi.nlm.nih.gov/pubmed/28362852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174998
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