Pharmacokinetics and Pharmacodynamics of Inorganic Nitrate in Heart Failure With Preserved Ejection Fraction

RATIONALE: Nitrate-rich beetroot juice has been shown to improve exercise capacity in Heart Failure with Preserved Ejection Fraction (HFpEF), but studies using pharmacologic preparations of inorganic nitrate are lacking. OBJECTIVES: To determine: (1) the dose-response effect of potassium nitrate (KN...

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Publicado no:Circ Res
Main Authors: Zamani, Payman, Tan, Victor, Soto-Calderon, Haideliza, Beraun, Melissa, Brandimarto, Jeffrey A., Trieu, Lien, Varakantam, Swapna, Doulias, Paschalis-Thomas, Townsend, Raymond R., Chittams, Jesse, Margulies, Kenneth B., Cappola, Thomas P., Poole, David C., Ischiropoulos, Harry, Chirinos, Julio A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376233/
https://ncbi.nlm.nih.gov/pubmed/27927683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.116.309832
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