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Characterizing the pocketome of Mycobacterium tuberculosis and application in rationalizing polypharmacological target selection

Polypharmacology is beginning to emerge as an important concept in the field of drug discovery. However, there are no established approaches to either select appropriate target sets or design polypharmacological drugs. Here, we propose a structural-proteomics approach that utilizes the structural in...

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書目詳細資料
發表在:Sci Rep
Main Authors: Anand, Praveen, Chandra, Nagasuma
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376175/
https://ncbi.nlm.nih.gov/pubmed/25220818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep06356
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