Ameliorating ER-stress attenuates Aeromonas hydrophila-induced mitochondrial dysfunctioning and caspase mediated HKM apoptosis in Clarias batrachus

Endoplasmic reticulum (ER)-stress and unfolding protein response (UPR) has not been implied in Aeromonas hydrophila-pathogenicity. We report increased expression of the ER-stress markers: CHOP, BiP and phospho-eIF2α in A. hydrophila-infected headkidney macrophages (HKM) in Clarias batrachus. Pre-tre...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Banerjee, Chaitali, Singh, Ambika, Das, Taposh Kumar, Raman, Rajagopal, Shrivastava, Anju, Mazumder, Shibnath
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2014
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376045/
https://ncbi.nlm.nih.gov/pubmed/25059203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05820
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