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Mechanism of progestin resistance in endometrial precancer/cancer through Nrf2-survivin pathway

Progestin is commonly used for young patients suffering from endometrial hyperplasia or cancer. However, there is approximately 30% failure rate with unclear mechanism. We investigated if Nrf2-survivin pathway contributes the progestin resistance (PR) in this setting. Current study detected Nrf2 and...

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Publicat a:Am J Transl Res
Autors principals: Fan, Rujia, Wang, Yiying, Wang, Yue, Wei, Li, Zheng, Wenxin
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376038/
https://ncbi.nlm.nih.gov/pubmed/28386373
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