Thioredoxin-2 protects against oxygen-glucose deprivation/reperfusion injury by inhibiting autophagy and apoptosis in H9c2 cardiomyocytes

The aim of this study is to examine the role of thioredoxin-2 (Trx2) in autophagy and apoptosis during myocardial ischemia-reperfusion (I/R) injury in vitro. We employed the oxygen-glucose deprivation and reperfusion (OGD/R) model of H9c2 cells and used lentiviral infection to overexpress Trx2. H9c2...

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Bibliografische gegevens
Gepubliceerd in:Am J Transl Res
Hoofdauteurs: Li, Yan-Yan, Xiang, Yin, Zhang, Song, Wang, Yan, Yang, Jie, Liu, Wei, Xue, Feng-Tai
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: e-Century Publishing Corporation 2017
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376037/
https://ncbi.nlm.nih.gov/pubmed/28386372
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