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Neuroprotective effect of miR-665 against sevoflurane anesthesia-induced cognitive dysfunction in rats through PI3K/Akt signaling pathway by targeting insulin-like growth factor 2

The aim of this study was to investigate the in vivo and in vitro effects of miR-665 on sevoflurane anesthesia-induced cognitive dysfunction. SH-SY5Y cells and male SD rats were treated with sevoflurane to simulate anesthesia-induced cognitive dysfunction. The cells and rats both were transfected wi...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Principais autores: Lu, Xihua, Lv, Shuaiguo, Mi, Yan, Wang, Lei, Wang, Gensheng
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376025/
https://ncbi.nlm.nih.gov/pubmed/28386360
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