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HIF-1α regulates Cx40-dependent vasodilatation following hemorrhagic shock in rats

HIF-1α plays an essential role in hemorrhagic shock-induced vasoconstriction. However, the underlying mechanisms remain poorly understood. Here, we studied both the role of HIF-1α in regulating vasodilatation, and the involvement of Cx40 in this process. We found that endothelium-dependent vasodilat...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Duan, Chenyang, Chen, Ken, Yang, Guangming, Li, Tao, Liu, Liangming
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376018/
https://ncbi.nlm.nih.gov/pubmed/28386353
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