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A Sequence-Independent, Unstructured Internal Ribosome Entry Site Is Responsible for Internal Expression of the Coat Protein of Turnip Crinkle Virus

To maximize the coding potential of viral genomes, internal ribosome entry sites (IRES) can be used to bypass the traditional requirement of a 5′ cap and some/all of the associated translation initiation factors. Although viral IRES typically contain higher-order RNA structure, an unstructured seque...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: May, Jared, Johnson, Philip, Saleem, Huma, Simon, Anne E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5375686/
https://ncbi.nlm.nih.gov/pubmed/28179526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02421-16
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