Lack of ADCC Breadth of Human Nonneutralizing Anti-HIV-1 Antibodies

Anti-human immunodeficiency virus type 1 (HIV-1) nonneutralizing antibodies (nnAbs) capable of antibody-dependent cellular cytotoxicity (ADCC) have been identified as a protective immune correlate in the RV144 vaccine efficacy trial. Broadly neutralizing antibodies (bNAbs) also mediate ADCC in cell...

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Vydáno v:J Virol
Hlavní autoři: Bruel, Timothée, Guivel-Benhassine, Florence, Lorin, Valérie, Lortat-Jacob, Hugues, Baleux, Françoise, Bourdic, Katia, Noël, Nicolas, Lambotte, Olivier, Mouquet, Hugo, Schwartz, Olivier
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5375671/
https://ncbi.nlm.nih.gov/pubmed/28122982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02440-16
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