Deciphering CaMKII Multimerization Using Fluorescence Correlation Spectroscopy and Homo-FRET Analysis

While kinases are typically composed of one or two subunits, calcium-calmodulin (CaM)-dependent protein kinase II (CaMKII) is composed of 8–14 subunits arranged as pairs around a central core. It is not clear if the CaMKII holoenzyme functions as an assembly of independent subunits, as catalytic pai...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Sarkar, Pabak, Davis, Kaitlin A., Puhl, Henry L., Veetil, Jithesh V., Nguyen, Tuan A., Vogel, Steven S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2017
Assuntos:
Cell Biophysics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5375141/
https://ncbi.nlm.nih.gov/pubmed/28355553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.02.005
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