Selecting high-quality negative samples for effectively predicting protein-RNA interactions

BACKGROUND: The identification of Protein-RNA Interactions (PRIs) is important to understanding cell activities. Recently, several machine learning-based methods have been developed for identifying PRIs. However, the performance of these methods is unsatisfactory. One major reason is that they usual...

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Bibliographic Details
Published in:BMC Syst Biol
Main Authors: Cheng, Zhanzhan, Huang, Kai, Wang, Yang, Liu, Hui, Guan, Jihong, Zhou, Shuigeng
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374704/
https://ncbi.nlm.nih.gov/pubmed/28361676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-017-0390-8
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