Bromodomain protein 4 discriminates tissue-specific super-enhancers containing disease-specific susceptibility loci in prostate and breast cancer

BACKGROUND: Epigenetic information can be used to identify clinically relevant genomic variants single nucleotide polymorphisms (SNPs) of functional importance in cancer development. Super-enhancers are cell-specific DNA elements, acting to determine tissue or cell identity and driving tumor progres...

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Vydáno v:BMC Genomics
Hlavní autoři: Zuber, Verena, Bettella, Francesco, Witoelar, Aree, Andreassen, Ole A., Mills, Ian G., Urbanucci, Alfonso
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374680/
https://ncbi.nlm.nih.gov/pubmed/28359301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-3620-y
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