Cerebrospinal fluid cell-free mitochondrial DNA is associated with HIV replication, iron transport, and mild HIV-associated neurocognitive impairment

BACKGROUND: Mitochondria are abundant organelles critical for energy metabolism and brain function. Mitochondrial DNA (mtDNA), released during cellular injury and as part of the innate immune response to viral pathogens, contains CpG motifs that act as TLR-9 ligands. We investigated relationships be...

Szczegółowa specyfikacja

Zapisane w:
Opis bibliograficzny
Wydane w:J Neuroinflammation
Główni autorzy: Mehta, Sanjay R., Pérez-Santiago, Josué, Hulgan, Todd, Day, Tyler R. C., Barnholtz-Sloan, Jill, Gittleman, Haley, Letendre, Scott, Ellis, Ronald, Heaton, Robert, Patton, Stephanie, Suben, Jesse D., Franklin, Donald, Rosario, Debralee, Clifford, David B., Collier, Ann C., Marra, Christina M., Gelman, Benjamin B., McArthur, Justin, McCutchan, Allen, Morgello, Susan, Simpson, David, Connor, James, Grant, Igor, Kallianpur, Asha
Format: Artigo
Język:Inglês
Wydane: BioMed Central 2017
Hasła przedmiotowe:
Research
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374652/
https://ncbi.nlm.nih.gov/pubmed/28359324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-0848-z
Etykiety: Dodaj etykietę
Nie ma etykietki, Dołącz pierwszą etykiete!

Podobne zapisy