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An integrated approach with new strategies for QSAR models and lead optimization

BACKGROUND: Computational drug design approaches are important for shortening the time and reducing the cost for drug discovery and development. Among these methods, molecular docking and quantitative structure activity relationship (QSAR) play key roles for lead discovery and optimization. Here, we...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Hsu, Hui-Hui, Hsu, Yen-Chao, Chang, Li-Jen, Yang, Jinn-Moon
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374651/
https://ncbi.nlm.nih.gov/pubmed/28361681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-3503-2
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