CK2 in Cancer: Cellular and Biochemical Mechanisms and Potential Therapeutic Target

CK2 genes are overexpressed in many human cancers, and most often overexpression is associated with worse prognosis. Site-specific expression in mice leads to cancer development (e.g., breast, lymphoma) indicating the oncogenic nature of CK2. CK2 is involved in many key aspects of cancer including i...

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Veröffentlicht in:Pharmaceuticals (Basel)
Hauptverfasser: Chua, Melissa M.J., Ortega, Charina E., Sheikh, Ayesha, Lee, Migi, Abdul-Rassoul, Hussein, Hartshorn, Kevan L., Dominguez, Isabel
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2017
Schlagworte:
Review
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374422/
https://ncbi.nlm.nih.gov/pubmed/28134850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph10010018
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