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Biomarker-Guided Non-Adaptive Trial Designs in Phase II and Phase III: A Methodological Review

Biomarker-guided treatment is a rapidly developing area of medicine, where treatment choice is personalised according to one or more of an individual’s biomarker measurements. A number of biomarker-guided trial designs have been proposed in the past decade, including both adaptive and non-adaptive t...

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Bibliographic Details
Published in:J Pers Med
Main Authors: Antoniou, Miranta, Kolamunnage-Dona, Ruwanthi, Jorgensen, Andrea L.
Format: Artigo
Language:Inglês
Published: MDPI 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374391/
https://ncbi.nlm.nih.gov/pubmed/28125057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jpm7010001
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