The assembly of developing motor neurons depends on an interplay between spontaneous activity, type II cadherins and gap junctions

A core structural and functional motif of the vertebrate central nervous system is discrete clusters of neurons or ‘nuclei’. Yet the developmental mechanisms underlying this fundamental mode of organisation are largely unknown. We have previously shown that the assembly of motor neurons into nuclei...

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Bibliographic Details
Published in:Development
Main Authors: Montague, Karli, Lowe, Andrew S., Uzquiano, Ana, Knüfer, Athene, Astick, Marc, Price, Stephen R., Guthrie, Sarah
Format: Artigo
Language:Inglês
Published: The Company of Biologists Ltd 2017
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Research Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374350/
https://ncbi.nlm.nih.gov/pubmed/28246212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.144063
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