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MicroRNAs in the etiology of colorectal cancer: pathways and clinical implications

MicroRNAs (miRNAs) are small single-stranded RNAs that repress mRNA translation and trigger mRNA degradation. Of the ∼1900 miRNA-encoding genes present in the human genome, ∼250 miRNAs are reported to have changes in abundance or altered functions in colorectal cancer. Thousands of studies have docu...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Strubberg, Ashlee M., Madison, Blair B.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374322/
https://ncbi.nlm.nih.gov/pubmed/28250048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.027441
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