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Sialic acid-to-urea ratio as a measure of airway surface hydration

Although airway mucus dehydration is key to pathophysiology of cystic fibrosis (CF) and other airways diseases, measuring mucus hydration is challenging. We explored a robust method to estimate mucus hydration using sialic acid as a marker for mucin content. Terminal sialic acid residues from mucins...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Esther, Charles R., Hill, David B., Button, Brian, Shi, Shuai, Jania, Corey, Duncan, Elizabeth A., Doerschuk, Claire M., Chen, Gang, Ranganathan, Sarath, Stick, Stephen M., Boucher, Richard C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374301/
https://ncbi.nlm.nih.gov/pubmed/28062483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00398.2016
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