MicroRNA-125a and -b inhibit A20 and MAVS to promote inflammation and impair antiviral response in COPD

Influenza A virus (IAV) infections lead to severe inflammation in the airways. Patients with chronic obstructive pulmonary disease (COPD) characteristically have exaggerated airway inflammation and are more susceptible to infections with severe symptoms and increased mortality. The mechanisms that c...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Hsu, Alan C-Y., Dua, Kamal, Starkey, Malcolm R., Haw, Tatt-Jhong, Nair, Prema M., Nichol, Kristy, Zammit, Nathan, Grey, Shane T., Baines, Katherine J., Foster, Paul S., Hansbro, Philip M., Wark, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374076/
https://ncbi.nlm.nih.gov/pubmed/28405612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.90443
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