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GM-CSF is not essential for experimental autoimmune encephalomyelitis but promotes brain-targeted disease

Experimental autoimmune encephalomyelitis (EAE) has been used as an animal model of multiple sclerosis to identify pathogenic cytokines that could be therapeutic targets. Granulocyte-macrophage colony-stimulating factor (GM-CSF) is the only cytokine reported to be essential for EAE. We investigated...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Pierson, Emily R., Goverman, Joan M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374070/
https://ncbi.nlm.nih.gov/pubmed/28405624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.92362
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