The NLRP3 inflammasome modulates sleep and NREM sleep delta power induced by spontaneous wakefulness, sleep deprivation and lipopolysaccharide

Both sleep loss and pathogens can enhance brain inflammation, sleep, and sleep intensity as indicated by electroencephalogram delta (δ) power. The pro-inflammatory cytokine interleukin-1 beta (IL-1β) is increased in the cortex after sleep deprivation (SD) and in response to the Gram-negative bacteri...

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Publicado no:Brain Behav Immun
Main Authors: Zielinski, Mark R., Gerashchenko, Dmitry, Karpova, Svetlana A., Konanki, Varun, McCarley, Robert W., Sutterwala, Fayyaz S., Strecker, Robert E., Basheer, Radhika
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373953/
https://ncbi.nlm.nih.gov/pubmed/28109896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2017.01.012
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