Genome-wide analysis identifies an African- specific variant in SEMA4D that is associated with Body Mass Index

OBJECTIVE: The prevalence of obesity varies between ethnic groups. No GWAS for BMI has been conducted in continental Africans. METHODS: We performed a GWAS for body mass index (BMI) in 1,570 West Africans (WA). Replication was conducted in independent samples of WA (n=1,411) and African Americans (A...

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Pubblicato in:Obesity (Silver Spring)
Autori principali: Chen, Guanjie, Doumatey, Ayo P., Zhou, Jie, Lei, Lin, Bentley, Amy R., Fasanmade, Olufemi, Okafor, Godfrey, Eghan, Benjamin, Agyenim-Boateng, Kofi, Amoah, Albert, Adebamowo, Clement, Acheampong, Joseph, Johnson, Thomas, Oli, Johnnie, Shriner, Daniel, Adeyemo, Adebowale A., Rotimi, Charles N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373947/
https://ncbi.nlm.nih.gov/pubmed/28296344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/oby.21804
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