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Tissue-specific exosome biomarkers for noninvasively monitoring immunologic rejection of transplanted tissue

In transplantation, there is a critical need for noninvasive biomarker platforms for monitoring immunologic rejection. We hypothesized that transplanted tissues release donor-specific exosomes into recipient circulation and that the quantitation and profiling of donor intra-exosomal cargoes may cons...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Vallabhajosyula, Prashanth, Korutla, Laxminarayana, Habertheuer, Andreas, Yu, Ming, Rostami, Susan, Yuan, Chao-Xing, Reddy, Sanjana, Liu, Chengyang, Korutla, Varun, Koeberlein, Brigitte, Trofe-Clark, Jennifer, Rickels, Michael R., Naji, Ali
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373894/
https://ncbi.nlm.nih.gov/pubmed/28319051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI87993
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