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Role of steroid receptor and coregulator mutations in hormone-dependent cancers

Steroid hormones mediate critical lineage-specific developmental and physiologic responses. They function by binding their cognate receptors, which are transcription factors that drive specific gene expression programs. The requirement of most prostate cancers for androgen and most breast cancers fo...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Groner, Anna C., Brown, Myles
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373886/
https://ncbi.nlm.nih.gov/pubmed/28368289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI88885
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