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Dicer is Required for the Maintenance of Notch Signaling and Gliogenic Competence During Mouse Retinal Development

MicroRNAs (miRNAs) are 19–25 nucleotide RNAs that regulate messenger RNA translation and stability. Recently, we performed a conditional knockout (CKO) of the miRNA-processing enzyme Dicer during mouse retinal development and showed an essential role for miRNAs in the transition of retinal progenito...

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Détails bibliographiques
Publié dans:Dev Neurobiol
Auteurs principaux: Georgi, Sean A., Reh, Thomas A.
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373852/
https://ncbi.nlm.nih.gov/pubmed/21542136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dneu.20899
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