Cadherins mediate cocaine-induced synaptic plasticity and behavioral conditioning

Drugs of abuse alter synaptic connections in the ‘reward circuit’ of the brain, which leads to long-lasting behavioral changes that underlie addiction. Here we show that cadherin adhesion molecules play a critical role in mediating synaptic plasticity and behavioral changes driven by cocaine. We dem...

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Bibliografske podrobnosti
izdano v:Nat Neurosci
Main Authors: Mills, Fergil, Globa, Andrea K., Liu, Shuai, Cowan, Catherine M., Mobasser, Mahsan, Phillips, Anthony G., Borgland, Stephanie L., Bamji, Shernaz X.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373847/
https://ncbi.nlm.nih.gov/pubmed/28192395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.4503
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