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Are outcomes reported in surgical randomized trials patient-important? A systematic review and meta-analysis

BACKGROUND: The dangers of using surrogate outcomes are well documented. They may have little or no association with their patient-important correlates, leading to the approval and use of interventions that lack efficacy. We sought to assess whether primary outcomes in surgical randomized controlled...

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Podrobná bibliografie
Vydáno v:Can J Surg
Hlavní autoři: Adie, Sam, Harris, Ian A., Naylor, Justine M., Mittal, Rajat
Médium: Artigo
Jazyk:Inglês
Vydáno: Joule Inc. 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373721/
https://ncbi.nlm.nih.gov/pubmed/28234219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1503/cjs.010616
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