Persistent gating deficit and increased sensitivity to NMDA receptor antagonism after puberty in a new mouse model of the human 22q11.2 microdeletion syndrome: a study in male mice

BACKGROUND: The hemizygous 22q11.2 microdeletion is a common copy number variant in humans. The deletion confers high risk for neurodevelopmental disorders, including autism and schizophrenia. Up to 41% of deletion carriers experience psychotic symptoms. METHODS: We present a new mouse model (Df(h22...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Psychiatry Neurosci
Main Authors: Didriksen, Michael, Fejgin, Kim, Nilsson, Simon R.O., Birknow, Michelle R., Grayton, Hannah M., Larsen, Peter H., Lauridsen, Jes B., Nielsen, Vibeke, Celada, Pau, Santana, Noemi, Kallunki, Pekka, Christensen, Kenneth V., Werge, Thomas M., Stensbøl, Tine B., Egebjerg, Jan, Gastambide, Francois, Artigas, Francesc, Bastlund, Jesper F., Nielsen, Jacob
Format: Artigo
Sprog:Inglês
Udgivet: Joule Inc. 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373712/
https://ncbi.nlm.nih.gov/pubmed/27391101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1503/jpn.150381
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker