High-accuracy haplotype imputation using unphased genotype data as the references

Enormously growing genomic datasets present a new challenge on missing data imputation, a notoriously resource-demanding task. Haplotype imputation requires ethnicity-matched references. However, to date, haplotype references are not available for the majority of populations in the world. We explore...

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Bibliographic Details
Published in:Gene
Main Authors: Li, Wenzhi, Xu, Wei, Fu, Guoxing, Ma, Li, Richards, Jendai, Rao, Weinian, Bythwood, Tameka, Guo, Shiwen, Song, Qing
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373555/
https://ncbi.nlm.nih.gov/pubmed/26232609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2015.07.082
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