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A growing animal model for neonatal repair of large diaphragmatic defects to evaluate patch function and outcome

OBJECTIVES: We aimed to develop a more representative model for neonatal congenital diaphragmatic hernia repair in a large animal model, by creating a large defect in a fast-growing pup, using functional pulmonary and diaphragmatic read outs. BACKGROUND: Grafts are increasingly used to repair congen...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Eastwood, Mary Patrice, Joyeux, Luc, Pranpanus, Savitree, Van der Merwe, Johannes, Verbeken, Eric, De Vleeschauwer, Stephanie, Gayan-Ramirez, Ghislaine, Deprest, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373533/
https://ncbi.nlm.nih.gov/pubmed/28358826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174332
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