A Randomized, Controlled Trial of Rituximab in IgA Nephropathy with Proteinuria and Renal Dysfunction

IgA nephropathy frequently leads to progressive CKD. Although interest surrounds use of immunosuppressive agents added to standard therapy, several recent studies have questioned efficacy of these agents. Depleting antibody–producing B cells potentially offers a new therapy. In this open label, mult...

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Vydáno v:J Am Soc Nephrol
Hlavní autoři: Lafayette, Richard A., Canetta, Pietro A., Rovin, Brad H., Appel, Gerald B., Novak, Jan, Nath, Karl A., Sethi, Sanjeev, Tumlin, James A., Mehta, Kshama, Hogan, Marie, Erickson, Stephen, Julian, Bruce A., Leung, Nelson, Enders, Felicity T., Brown, Rhubell, Knoppova, Barbora, Hall, Stacy, Fervenza, Fernando C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Nephrology 2017
Témata:
Clinical Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373458/
https://ncbi.nlm.nih.gov/pubmed/27821627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016060640
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