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APOL1–Mediated Cell Injury Involves Disruption of Conserved Trafficking Processes

APOL1 harbors C–terminal sequence variants (G1 and G2), which account for much of the increased risk for kidney disease in sub–Saharan African ancestry populations. Expression of the risk variants has also been shown to cause injury to podocytes and other cell types, but the underlying mechanisms ar...

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書目詳細資料
發表在:J Am Soc Nephrol
Main Authors: Kruzel-Davila, Etty, Shemer, Revital, Ofir, Ayala, Bavli-Kertselli, Ira, Darlyuk-Saadon, Ilona, Oren-Giladi, Pazit, Wasser, Walter G., Magen, Daniella, Zaknoun, Eid, Schuldiner, Maya, Salzberg, Adi, Kornitzer, Daniel, Marelja, Zvonimir, Simons, Matias, Skorecki, Karl
格式: Artigo
語言:Inglês
出版: American Society of Nephrology 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373454/
https://ncbi.nlm.nih.gov/pubmed/27864431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016050546
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