APOL1–Mediated Cell Injury Involves Disruption of Conserved Trafficking Processes

APOL1 harbors C–terminal sequence variants (G1 and G2), which account for much of the increased risk for kidney disease in sub–Saharan African ancestry populations. Expression of the risk variants has also been shown to cause injury to podocytes and other cell types, but the underlying mechanisms ar...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Kruzel-Davila, Etty, Shemer, Revital, Ofir, Ayala, Bavli-Kertselli, Ira, Darlyuk-Saadon, Ilona, Oren-Giladi, Pazit, Wasser, Walter G., Magen, Daniella, Zaknoun, Eid, Schuldiner, Maya, Salzberg, Adi, Kornitzer, Daniel, Marelja, Zvonimir, Simons, Matias, Skorecki, Karl
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2017
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373454/
https://ncbi.nlm.nih.gov/pubmed/27864431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016050546
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