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APOL1–Mediated Cell Injury Involves Disruption of Conserved Trafficking Processes
APOL1 harbors C–terminal sequence variants (G1 and G2), which account for much of the increased risk for kidney disease in sub–Saharan African ancestry populations. Expression of the risk variants has also been shown to cause injury to podocytes and other cell types, but the underlying mechanisms ar...
Zapisane w:
| Wydane w: | J Am Soc Nephrol |
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| Główni autorzy: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society of Nephrology
2017
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5373454/ https://ncbi.nlm.nih.gov/pubmed/27864431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016050546 |
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