APOL1–Mediated Cell Injury Involves Disruption of Conserved Trafficking Processes

APOL1 harbors C–terminal sequence variants (G1 and G2), which account for much of the increased risk for kidney disease in sub–Saharan African ancestry populations. Expression of the risk variants has also been shown to cause injury to podocytes and other cell types, but the underlying mechanisms ar...

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Detalles Bibliográficos
Publicado en:J Am Soc Nephrol
Autores principales: Kruzel-Davila, Etty, Shemer, Revital, Ofir, Ayala, Bavli-Kertselli, Ira, Darlyuk-Saadon, Ilona, Oren-Giladi, Pazit, Wasser, Walter G., Magen, Daniella, Zaknoun, Eid, Schuldiner, Maya, Salzberg, Adi, Kornitzer, Daniel, Marelja, Zvonimir, Simons, Matias, Skorecki, Karl
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Nephrology 2017
Materias:
Basic Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373454/
https://ncbi.nlm.nih.gov/pubmed/27864431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016050546
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