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Toll-Like Receptor 9 Stimulation Induces Aberrant Expression of a Proliferation-Inducing Ligand by Tonsillar Germinal Center B Cells in IgA Nephropathy

The TNF family member a proliferation-inducing ligand (APRIL; also known as TNFSF13), produced by myeloid cells, participates in the generation and survival of antibody–producing plasma cells. We studied the potential role of APRIL in the pathogenesis of IgA nephropathy (IgAN). We found that a signi...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Muto, Masahiro, Manfroi, Benoit, Suzuki, Hitoshi, Joh, Kensuke, Nagai, Masaaki, Wakai, Sachiko, Righini, Christian, Maiguma, Masayuki, Izui, Shozo, Tomino, Yasuhiko, Huard, Bertrand, Suzuki, Yusuke
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373453/
https://ncbi.nlm.nih.gov/pubmed/27920152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016050496
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