Sensing of cell stress by human γδ TCR-dependent recognition of annexin A2

Human γδ T cells comprise a first line of defense through T-cell receptor (TCR) recognition of stressed cells. However, the molecular determinants and stress pathways involved in this recognition are largely unknown. Here we show that exposure of tumor cells to various stress situations led to tumor...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Marlin, Romain, Pappalardo, Angela, Kaminski, Hannah, Willcox, Carrie R., Pitard, Vincent, Netzer, Sonia, Khairallah, Camille, Lomenech, Anne-Marie, Harly, Christelle, Bonneville, Marc, Moreau, Jean-François, Scotet, Emmanuel, Willcox, Benjamin E., Faustin, Benjamin, Déchanet-Merville, Julie
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2017
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373368/
https://ncbi.nlm.nih.gov/pubmed/28270598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1621052114
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