Pathogenic Huntington Alters BMP Signaling and Synaptic Growth through Local Disruptions of Endosomal Compartments

Huntington's disease (HD) is a neurodegenerative disorder caused by expansion of a polyglutamine (polyQ) stretch within the Huntingtin (Htt) protein. Pathogenic Htt disrupts multiple neuronal processes, including gene expression, axonal trafficking, proteasome and mitochondrial activity, and in...

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Xehetasun bibliografikoak
Argitaratua izan da:J Neurosci
Egile Nagusiak: Akbergenova, Yulia, Littleton, J. Troy
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Society for Neuroscience 2017
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373127/
https://ncbi.nlm.nih.gov/pubmed/28235896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2752-16.2017
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