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Histone Lysine-to-Methionine Mutations Reduce Histone Methylation and Cause Developmental Pleiotropy

Epigenetic modifications play critical roles in diverse biological processes. Histone Lys-to-Met (K-to-M) mutations act as gain-of-function mutations to inhibit a wide range of histone methyltransferases and are thought to promote tumorigenesis. However, it is largely unknown whether K-to-M mutation...

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Detalhes bibliográficos
Publicado no:Plant Physiol
Main Authors: Sanders, Dean, Qian, Shuiming, Fieweger, Rachael, Lu, Li, Dowell, James A., Denu, John M., Zhong, Xuehua
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Plant Biologists 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373047/
https://ncbi.nlm.nih.gov/pubmed/28202597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1104/pp.16.01499
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