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Interleukin 1 induces early protein phosphorylation and requires only a short exposure for late induced secretion of beta-endorphin in a mouse pituitary cell line.

Previous work has shown that prolonged pretreatment of a mouse anterior pituitary cell line, AtT-20 cells, with the cytokine interleukin 1 (IL-1) stimulates beta-endorphin release and potentiates the secretion induced by many secretagogues. Desensitization of protein kinase C (PKC) by pretreatment w...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Făgărăşan, M O, Bishop, J F, Rinaudo, M S, Axelrod, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1990
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53728/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2157204/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.7.2555
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